Protocol Service
Female Hormone Optimization
Estrogen and Progesterone Therapy in Scarsdale, NY
Protocol Health prescribes combined estrogen and progesterone therapy, the standard HRT for women with a uterus, at our Scarsdale, NY clinic and by telehealth: transdermal estradiol for symptoms and bone, oral micronized progesterone to protect the uterine lining.
Consultation $249, or $349 with blood work.
Transdermal estradiol and oral micronized progesterone are available as FDA-approved products; compounded hormones are not FDA-approved.
Medically reviewed by Richard Dentico, MD, Medical Director
★ 5.0 on Google · 107 reviews (as of October 2026) · Physician-led, family-owned
Our Scarsdale clinic serves Westchester County (HRT for women in Westchester). Telehealth in NY, NJ, CT, FL and CA.
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Estrogen + Oral Progesterone at Protocol Health
Before you book
The combination most women with a uterus need
Estradiol treats hot flashes, night sweats and bone loss; progesterone protects the uterine lining from estrogen. Together, FDA-approved transdermal estradiol and oral micronized progesterone cover what custom compounding promises, bioidentical molecules and adjustable doses, with a far larger evidence base.
Who is combined HRT for?
Women with a uterus and bothersome menopause symptoms.
- Hot flashes, night sweats or poor sleep
- A uterus
- Under 60 or within 10 years of menopause, ideally
- No history of breast cancer, clots or stroke without careful discussion
Safety in context
The 2025 FDA label change and timing matter.
Boxed warnings. In November 2025 the FDA began removing the broad boxed warnings on menopausal HRT and approved the first six revised labels in February 2026, keeping the endometrial warning on estrogen-alone products.
Timing. For healthy women under 60 or within 10 years of menopause, benefits generally outweigh risks.
Route. Transdermal estradiol carries a lower clot risk than oral estrogen.
What the combination does
Symptoms. Estradiol for hot flashes and night sweats.
Bone. Estrogen helps prevent bone loss.
Lining protection. Progesterone protects the uterus.
Monitored. Adjusted as symptoms change.
Starting combined HRT
In the Scarsdale clinic or by telehealth where appropriate.
- Evaluation. Symptoms, history, when periods stopped.
- Labs. To rule out look-alikes.
- Plan. Estradiol route and progesterone schedule.
- Follow-up. Adjusted over time.
Common questions
Estrogen + Oral Progesterone: frequently asked questions
Why both hormones?
Estrogen treats symptoms; progesterone protects the uterine lining.
Are these bioidentical?
Estradiol and micronized progesterone are bioidentical and available as FDA-approved products.
Is combined HRT safe?
For healthy women under 60 or within 10 years of menopause, the Menopause Society concludes benefits generally outweigh risks.
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