Protocol Service
Female Hormone Optimization
Estradiol Gel and Cream in Scarsdale, NY
Protocol Health prescribes estradiol gel or cream, a daily topical form of estrogen for perimenopause and menopause symptoms, at our Scarsdale, NY clinic and by telehealth. It works like the patch, through the skin, with daily rather than weekly dosing.
Consultation $249, or $349 with blood work.
FDA-approved estradiol gels exist; compounded estrogen creams are not FDA-approved.
Medically reviewed by Richard Dentico, MD, Medical Director
★ 5.0 on Google · 107 reviews (as of October 2026) · Physician-led, family-owned
Our Scarsdale clinic serves Westchester County (HRT for women in Westchester). Telehealth in NY, NJ, CT, FL and CA.
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Estrogen Cream / Gel at Protocol Health
Before you book
Gel or cream versus the patch
Estradiol gel or cream is rubbed into the skin each day. Like the patch, it goes through the skin rather than the liver. Some women prefer it to a patch because there is nothing to stick on; others prefer the patch because there is nothing to remember daily.
Who is estradiol gel for?
Women who want transdermal estrogen without a patch.
- Bothersome hot flashes or night sweats
- Skin irritation from patches
- Comfortable with a daily routine
- Have had a risk review
What to know before starting
Daily use, and care around others.
Progesterone. With a uterus, progesterone is needed.
Daily habit. Missed days mean symptoms can return.
FDA-approved or compounded. Your provider explains which product you are getting.
Why women choose a topical
No adhesive. Nothing stays on the skin.
Adjustable. The daily amount can be changed in small steps.
Through the skin. The transdermal route skips the liver.
Same benefits. Treats hot flashes and night sweats and protects bone.
Starting estradiol gel or cream
In the Scarsdale clinic or by telehealth where appropriate.
- Evaluation. Symptoms and history.
- Labs. To rule out other causes.
- Prescription. Gel or cream, dose, and progesterone if needed.
- Follow-up. Adjusted to symptoms.
Common questions
Estrogen Cream / Gel: frequently asked questions
Is estradiol gel FDA-approved?
FDA-approved estradiol gels exist; compounded estrogen creams are not FDA-approved.
Gel or patch: which is better?
Neither for everyone. Both go through the skin; the choice is routine and skin comfort.
Do I need progesterone?
If you have a uterus and use systemic estrogen, yes.
Get started
Talk to a provider about topical estrogen
Start with the short intake.
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