Protocol Service
Peptide Therapy
Wolverine Stack (BPC-157 + TB-500) in Scarsdale, NY
The Wolverine Stack pairs two recovery peptides, BPC-157 and TB-500. Protocol Health prescribes it at our Scarsdale, NY clinic only under physician supervision, after explaining that neither peptide is FDA-approved and that human data on the combination amount to four patients.
Consultation $249, or $349 with blood work.
BPC-157 and TB-500 have never been FDA-approved for any use, so prescribing them is unapproved use, not off-label use. The FDA has flagged both, when compounded, for possible immune reactions and impurities.
Medically reviewed by Richard Dentico, MD, Medical Director
★ 5.0 on Google · 107 reviews (as of October 2026) · Physician-led, family-owned
Our Scarsdale clinic serves Westchester County. Telehealth in NY, NJ, CT, FL and CA.
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Wolverine Stack (BPC-157 and TB-500) at Protocol Health
Before you book
What is in the Wolverine Stack?
BPC-157 is a 15-amino-acid peptide derived from a gastric protein; TB-500 is a fragment of thymosin beta-4. Each has consistent animal data on tendon, ligament and muscle healing. The combination is popular, but the human data on using them together amount to four patients, so it is a decision to make with eyes open.
Who asks about the Wolverine Stack?
Active adults with a soft-tissue injury who accept that the evidence is mostly animal studies.
- A tendon, ligament or muscle problem under rehab
- Not subject to sports drug testing
- Want physician oversight
- Accept very limited human evidence
The Wolverine Stack evidence in one place
Animal data for each peptide, almost none for people.
BPC-157. A 2025 systematic review found no clinical safety data in humans.
TB-500. The FDA says it has not identified human exposure data.
Together. Human data on the combination: four patients.
How the stack is used here
Physician supervision. Prescribed only after an evaluation, never from a dosage chart.
With rehab. An adjunct to a recovery plan, not a replacement.
Alternatives compared. PRP and shockwave are considered at the same visit.
Sports testing flagged. BPC-157 is on the World Anti-Doping Agency's prohibited list.
Deciding on the stack
Evaluation, comparison, decision.
- Evaluation. The injury and what has been tried.
- Comparison. The stack against PRP, shockwave and rehab alone.
- Decision. Prescribed only if a provider judges it appropriate.
- Review. Progress checked with the rehab plan.
Common questions
Wolverine Stack (BPC-157 and TB-500): frequently asked questions
What is the Wolverine Stack?
A combination of the peptides BPC-157 and TB-500, used for soft-tissue recovery.
Is the Wolverine Stack FDA-approved?
No. Neither BPC-157 nor TB-500 has ever been FDA-approved for any use.
Is there human evidence for the combination?
Very little: the human data on the combination amount to four patients.
Can athletes use it?
BPC-157 is on the World Anti-Doping Agency's prohibited list, so tested athletes should not.
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